Hawaii & Mid-Pacific laboratory expertise

Advanced laboratory expertise.
Practical solutions.

Kokua Analytical Consultants brings technical depth to complex laboratory challenges—from LC-MS/MS methods and quality systems to applied R&D, environmental projects, and academic collaboration.

Clinical toxicologyLC-MS/MSApplied R&DEnvironmental projectsAcademic partnerships

What we do

Scientific support across the laboratory lifecycle.

Direct access to experienced laboratory professionals—with recommendations shaped around your instruments, people, and operating reality.

01

Laboratory operations

Technical oversight, quality systems, laboratory startup, corrective action, inspection readiness, and operational improvement.

QA & complianceStartup supportTechnical oversight
02

LC-MS/MS services

Method development, validation, optimization, instrument comparison, troubleshooting, and defensible technical documentation.

Method validationTroubleshootingOptimization
03

Quality & implementation

Practical QA review, competency programs, SOP development, regulatory readiness, software workflows, and implementation support.

Quality systemsSOPsCompetency
04

Research & development

Targeted analytical projects, method transfer, research-use workflows, grant collaboration, and academic-to-commercial translation.

Applied R&DMethod transferGrant support
05

Environmental projects

Method development and research support for water, emerging contaminants, marine toxins, natural products, and environmental matrices.

PFAS R&DMarine scienceScreening research
06

Education partnerships

Faculty research support, student projects, internships, guest instruction, LC-MS/MS workshops, and workforce-development programs.

UniversitiesSchoolsWorkforce training
Affiliated laboratory supportDILIGENT LABS

Consulting connected to the bench

Move from a technical plan to hands-on analytical work.

Kokua projects can be supported through Diligent Labs, an affiliated Hawaii laboratory platform focused on research-use analytical work, environmental method development, instrument workflows, and academic collaboration.

  • R&D and research-use analytical projects
  • Method development, transfer, validation, and troubleshooting
  • Environmental screening research and workflow development
  • Instrument evaluation, demonstrations, and technical training
Visit Diligent Labs Project availability depends on scope and readiness. Work requiring clinical licensure or environmental accreditation is coordinated with appropriately qualified laboratories.

Research & collaboration

Applied science for the Pacific and beyond.

Kokua connects analytical chemistry, laboratory operations, and real-world implementation to help research and education partners move promising ideas forward.

R&D

Analytical development

Targeted quantitative methods, small-molecule and pharmaceutical projects, method transfer, feasibility studies, and academic-to-commercial translation.

  • Method development and validation
  • Grant and contract collaboration
  • Research-use analytical support
ENV

Environmental projects

Research and method-development support for emerging contaminants and complex Pacific environmental questions.

  • PFAS and emerging-contaminant R&D
  • Water and environmental matrices
  • Marine toxins, microalgae, and natural products
EDU

Universities & schools

Industry-partner support for faculty research, student learning, workforce development, and collaborative funding opportunities.

  • Faculty and student research projects
  • Internships, guest lectures, and workshops
  • LC-MS/MS and laboratory-quality training

Government & public sector

Capability-driven support for public missions.

Kokua supports federal, state, military, and public-sector organizations with vendor-independent laboratory consulting, applied analytical research, environmental method development, technical training, and project-specific subcontract support.

Hawaii · Mid-Pacific · Nationwide
01

Laboratory & analytical support

Quality systems, technical oversight, LC-MS/MS methods, troubleshooting, validation planning, and equipment implementation.

02

Environmental & exposure R&D

Research planning and analytical-method support for emerging contaminants, environmental matrices, toxic exposures, and Pacific-specific priorities.

03

Training & workforce development

Technical workshops, competency programs, SOP development, instrument training, and university or agency workforce partnerships.

04

Prime & subcontract collaboration

Specialized technical support, proposal collaboration, scoped deliverables, and qualified teaming partners when certifications or additional disciplines are required.

Planning a public-sector laboratory, research, environmental, or training project?

Discuss a government project

How we work

One technical partner from first plan to sustained performance.

Kokua works alongside laboratory leaders, scientists, faculty, students, and project teams to turn complex requirements into a clear, workable path.

  1. 01Plan
  2. 02Build
  3. 03Validate
  4. 04Implement
  5. 05Monitor
  6. 06Improve

Featured capabilities

Support built around real laboratory problems.

01

LC-MS/MS method validation

Accuracy, precision, sensitivity, specificity, linearity, carryover, stability, interference, and final reporting.

02

Technical & quality oversight

QA review, calibration and QC trending, competency, corrective action, and practical quality-system support.

03

Instrument troubleshooting

Structured investigation of sensitivity loss, failed tuning, contamination, ion-ratio issues, and acquisition errors.

04

Laboratory startup

Workflow planning, test-menu design, equipment implementation, SOPs, training, validation, and readiness support.

05

Applied R&D

Targeted quantitative analysis, research-use methods, small-molecule projects, method transfer, and technical collaboration.

06

Environmental development

Research and screening workflows for emerging contaminants, water, marine toxins, natural products, and environmental matrices.

07

Academic partnerships

Faculty research, student projects, internships, workshops, workforce development, and collaborative grant support.

08

Technology translation

Laboratory software and automation workflows, AI-assisted QA/QC concepts, commercialization planning, and implementation.

Who we help

Practical technical depth for laboratories, researchers, and educators.

Hawaii-based, serving the Mid-Pacific and organizations nationwide with vendor-independent guidance shaped to each program.

01Clinical laboratories
02Reference laboratories
03Physician organizations
04Universities & research
05Schools & workforce programs
06Environmental organizations
07Federal, state & military
08Commercial laboratories
Michael Twilbeck, founder of Kokua Analytical Consultants

Leadership

Scientific expertise grounded in implementation.

Led by Michael Twilbeck, Kokua Analytical brings more than a decade of experience across clinical toxicology, LC-MS/MS, laboratory operations, method validation, quality systems, technical oversight, troubleshooting, applied research, and staff development. Michael is also a co-owner of Diligent Labs.

Hawaii & Pacific rootedLocal perspective and direct access
Nationwide reachOn-site and remote project support
Vendor independentRecommendations built around your needs

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Let's solve your laboratory or research challenge.